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Letters are the first residues of human EGFR (UniProt P00533), used as index marks.
Afraim Boshra
Medical Biotechnology student building toward computational proteomics and protein design.
Explore EGFR projectGitHubDownload CV
- Public repositories listed
- 3
- EGFR modules
- 1 in progress · 10 planned
cGPA 3.87/4.00 · top 3 of cohort
Computational proteomics / protein designA sequence of interests.
Primary structure
Medical Biotechnology student at Badr University in Cairo, building toward computational proteomics and protein design. Current work spans an EGFR research plan, biology-themed Python problems, R analysis, and bioinformatics algorithms practice.
Afraim Mario Mokhtar Boshra
Education
B.Sc. Medical Biotechnology
Badr University in Cairo
Sep 2024 – Sep 2028 (expected)
cGPA 3.87/4.00
Level 3
Top 3 of cohort for three consecutive semesters.
Tools, with context.
Secondary structure
Hands-on · no public link yetUsed in shipped workLearning / in progressConceptual familiarityPlanned
Public evidence supports shipped work; hands-on practice without a public link, learning, planned work, and conceptual familiarity are shown separately, even without evidence.
Computational practice
Learning & exploration
Wet lab
Design & communication
LanguagesArabic · nativeEnglish · fluent, professionalFrench · basic
From foundations to research.
Tertiary structure
Planning complete · scaffolding in progress
EGFR Integrative Proteogenomics
Ten-module computational study of human EGFR (UniProt P00533): evolutionary conservation, transcriptomics, PTM network, re-analysis of public PRIDE proteomics data, structural characterization, and the mechanism of clinical resistance mutations (L858R, T790M; erlotinib → osimertinib).
No analysis results yet. No preprint.
Target: a bioRxiv preprint.
Explore EGFR projectModule plan
Repository setup + 10 planned modules
In progressPlannedComplete
Hover, focus or tap a module. Use arrow keys, Home or End.
Repository scaffolding
Reproducible repository layout, pinned environment, and a shared analysis package.
Explore EGFR projectRepositories
01Python / CS50P
protein-python-foundations
Original biology-themed problems built lecture-by-lecture alongside CS50P (lectures 0–8), plus two capstones: a SQLite DNA/protein sequence database CLI and a FASTA batch analyzer.
02R / ggplot2 / Quarto
protein-r-foundations
Six R checkpoints and a published Quarto report on amino-acid physicochemical properties, including hydropathy of the EGFR kinase domain.
03Algorithms / Python
Bioinformatics algorithms practice
Rosalind problems in standard-library Python: alignment, assembly, phylogenetics, and peptide inference.
Projects
2026–present
Synapse
Founder & Product Owner
Conceived and directed an online course platform for Egyptian Medical Biotechnology students: catalog, protected video delivery, quizzes, payment verification, and admin tools.
AI-assisted development: defined requirements and design, assembled and deployed the platform, tested and debugged.
Launching Fall 2026; will manage the platform and teach its Human Genome course.
2025
HCV Awareness Project
Team lead · product direction
Led a 9-person student team, supervised by Dr. Radwa Lutfy. Researched the medical content, designed the brochure, specified the companion site, and delivered most of the faculty presentation.
Companion website: conceived and directed with AI-assisted development.
Rated Excellent (A+) by all evaluating professors.
Visit websiteLive bench
Try the checkpoints in your browser
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Structure Lab
Sequence properties, in context
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Science is an assembly.
Quaternary structure
Leadership
Sep 2025–present
Head of Design & Marketing
Scientific Society for Biotechnology Students (SSBS), Badr University
Member (Sep 2025) → Vice Leader (Oct 2025) → Head (Feb 2026). Leads designers and marketing agents; helped organize Orientation Day 2026 (~500 students).
Jun 2025–present
Educational content creator
YouTube · Afraim’s 101 Courses
Long-form Arabic science lectures with original illustrations and narration.
Nov 2025–Jan 2026
Junior Teaching Assistant
TLC program
Taught genetics and cell biology to 5 Level-1 students (one placed 9th in her cohort).
Achievements
Three certificates: 3rd among Level-2 students, SOLE 4th place, and recognition as one of the 10 top junior TAs of ~100; the only student to receive all three.
Coursework
CS50P
Harvard
Completed with certificate.
Data Science: R Basics
HarvardX
All content and quizzes completed. Audit track; no verified certificate.
Bioinformatic Methods I & II
University of Toronto · Coursera
In progress.
Genome Editing workshop
Apr 2025
CRISPR-Cas9, qPCR, microscopy, and gels.
Echoes of Our Ancestors workshop
Nov 2025
Ancient DNA and the Egyptian Genome Project.
Let’s connect.
Contact
afraim.mario@outlook.com